EVO Screening Kits

Evolved enzymes.
Ready to screen.
Today.

Three kits built around our best evolved biocatalysts — unique variants engineered in our lab after years of research. Run the assay yourself or send us your substrate and we’ll do it for you.

3

kit families
available

16

evolved variants
per kit

20+

peer-reviewed
publications

100mg→kg

scale-up
available
Available kits

EVO UPOkit 3.0
16 evolved peroxygenases · C–H oxyfunctionalization · Pharma and Chemistry

EVO LACkit
16 evolved laccases · O₂ oxidation · Multi-sector

EVO CUTinase Cocktail
Multi-enzyme blend · Plastic degradation · Circular economy

Not sure which kit fits your substrate? Send it to us — we run the assay and deliver a full report.

What makes these kits different

Engineered, not isolated.
Documented, not just claimed.

Evolved in our lab

Every variant in our kits has been engineered through directed evolution — not sourced from databases or wild-type isolates.

Backed by 20+ publications

Performance documented in JACS, Angewandte Chemie and ACS journals — not just internal claims. Peer-reviewed science behind every variant. 3 patents.

A clear path to scale

Kits are the entry point — not the end point. Found a hit? We supply bulk quantities from 100 mg to kg, or run a custom directed evolution campaign to push it further.

Scientific support included

Step-by-step protocol, positive controls, and direct access to our scientists — not a call centre. We help you get results.

From screening to scale

The kit is the
first step.

Step 1

Order your kit

Choose based on your reaction type or target substrate

You are here
Step 2

Screen

In your lab with our protocol — or send us your substrate

Flexible
Step 3

Find your hit

Identify the variant with the best activity on your substrate

Screening output
Step 4

Scale or evolve

Bulk supply 100 mg → kg, or custom directed evolution to push it further

Your choice

OXYFUNCTIONALIZATION · PHARMA · FINE CHEM

NEW

EVO UPOkit 3.0

“P450 chemistry. H₂O simplicity.” — 16 evolved peroxygenases for selective C-H functionalization.

16UPO variants
160reactions
H₂O₂sole oxidant

 

KEY REACTIONS

 

Hydroxylations Epoxidations
O/N-dealkylations S-oxidations Brominations

 

APPLICATIONS

 

  • Human drug metabolites

  • Late-stage functionalization

  • Fine chemistry

  • New-to-nature chemistry

 

KIT CONTENTS

 

  • 16 evolved UPO variants (lyophilized)

  • Reaction buffer · H₂O₂ solution

  • Step-by-step protocol + positive controls

  • 160 reactions per kit

Published basis:

Gomez de Santos et al., JACS 145(6), 3443–3453 (2023) · Sánchez-Moreno et al., ACS Chem. Biol. 19(10) (2024) · Angewandte Chemie e202217372 (2022) & more

Talk to our team

GREEN OXIDATION · MULTI-SECTOR

EVO LACkit

“O₂ in. Water out. Nothing else needed.” — 16 high-redox potential evolved laccases.

16laccase variants
96reactions
O₂sole oxidant

 

REDOX MEDIATORS INCLUDED

 

HBT — H-atom transfer · High-redox substrates · Dyes & aromatics
TEMPO — Ionic mechanism · Alcohol oxidation · Carbohydrates
ABTS — Electron transfer · Broad substrate · Bioremediation

 

APPLICATIONS

 

Bioremediation Organic synthesis Textile Biosensors Biofuel cells

 

KIT CONTENTS

 

  • 16 evolved laccase variants (lyophilized)

  • 3 mediators: HBT, TEMPO, ABTS

  • 96-well plate format

  • Step-by-step protocol + positive controls

Published basis:

Matejček et al., ACS Catalysis 9: 4561–4572 (2019) · Gómez-Fernández et al., Appl. Environ. Microbiol. 86(14) (2020)

Talk to our team

PLASTIC DEGRADATION · CIRCULAR ECONOMY

EVO CUTinase Cocktail

“Plastics into monomers. Enzymatically.” — Multi-enzyme blend of evolved cutinases.

>3kU p-NPB activity
200reactions
pH 8mild conditions

 

TARGET POLYMERS

 

PET PEF PBS · PBAT Polyurethane Ester polymers

 

WHY A COCKTAIL?

 

Multiple evolved cutinases with complementary properties — broader polymer coverage, synergistic activity, more robust across conditions than any single variant.

 

KIT CONTENTS

 

  • Lyophilized CUTinase Cocktail (>3000 U p-NPB)

  • Reaction buffer

  • Step-by-step protocol

  • 200 reactions per kit

Published basis:

Dolz, Monterrey, Alcalde et al., ACS Omega 9(45), 45633–45640 (2024). Further data on request.

Talk to our team

Beyond the kit

Found your enzyme.
Here’s what comes next.

In-house testing service

Send us your substrate — we run the screening assay at our facilities and deliver a full activity report with the best candidates identified for your application.

Bulk enzyme supply

Order individual hit variants from 100 mg to kg scale — produced in our yeast expression system with CoA and full technical documentation. Delivered with ongoing support.

Custom directed evolution

Need the hit variant to perform even better? We run a tailored directed evolution campaign to push thermostability, activity, selectivity or expression yield further.

Not sure which kit
fits your substrate?

Tell us about your substrate and application — our scientists will recommend the best starting point. No commitment required.