Eco Friendly alternatives
FUNGAL UNSPECIFIC PEROXYGENASES (UPOs)
Peroxygenases are enzymes that perform complex C-H oxyfunctionalizations with a high degree of selectivity, simply triggered by hydrogen peroxide. The broad portfolio of reactions performed by UPOs, along with their less demanding requirements, place these enzymes in a unique position to drive a variety of particularly innovative chemical reactions.
EvoEnzyme has its own collection of evolved peroxygenases and mutant libraries ( WO/2017/081355) that can be put to use in the pharmaceutical and chemical industries.
To learn more?, see some of our publications: Gomez de Santos et al. 2018. ACS Catal 8: 4789-4799 ( https://doi.org/10.1021/acscatal.8b01004); Ramirez-Escudero et al. 2018. ACS Chem. Biol. 13: 3259-3268 (https://doi.org/10.1021/acschembio.8b00500); Martin-Diaz et al. 2018. Appl. Environ. Microb. 84: e00808-18 (https://doi.org/10.1128/AEM.00808-18); Molina-Espeja et al. 2016. ChemBioChem 17: 341-349 (http://doi.org/10.1002/cbic.201500493); Molina-Espeja et al. 2014. Appl. Environ. Microb. 80: 3496-3507 (http://dx.doi.org/10.1128/AEM.00490-14)